Protein-DNA interactions within a region of the LDL receptor promoter involved in sterol-mediated feedback repression of transcription were examined using in vivo genomic footprinting with dimethylsulfate (DMS).A broad region of protein-DNA contacts spanning from repeat 1 to beyond the transcription start sites was observed in primary cultures of h
Most surviving runic inscriptions from early medieval England were produced in an ecclesiastical context, and the influence of manuscript writing practices on the runic tradition can clearly be discerned.The manuscript record of runes or runica manuscripta that flourished particularly in the context of Anglo-Saxon missionary activity to the Contine
This paper explores the stages of organization and equipping that occurred in the communications of the Romanian army and Accessories the creation of the first specialized sub-units, preparation and participation in the War of Independence (1877- 1878) with further developments until the First World War.The study and analysis of the most significan
Abstract Background Patients who engage in Advance Care Planning (ACP) are more likely to get care consistent with their values.We Neck duster sought to determine the barriers and facilitators to ACP engagement after discharge from hospital.Methods Prior to discharge from hospital eligible patients received a standardized conversation about prognos